WASPS sensation Jack Willis will make his full England debut at Twickenham against Georgia.
The Premiership's 2020 player-of-the-season and players' player will be unleashed at open-side in a menacing back-row alongside Maro Itoje.
Reading-born rucker Willis, 23, has been on fire this year – having battled back from horrific ankle and knee injuries that ruined his first call-up to tour South Africa back in 2018.
Bristol Bears playmaker Max Malins, on loan from relegated Saracens, is also set for his first taste of Test match action from off the bench.
Boss Eddie Jones said: "We know there are a lot of expectations on us and we’ve applied ourselves hard and put a lot of pressure on ourselves in the early part of this week.
“Georgia will be a tough opponent, so we have a team with some real power in midfield.
"We have a good mix of youth and experience across the squad and they are completely focused on putting in an excellent performance on Saturday.
“We’re looking forward to being back at our home at Twickenham, we are humbled by the opportunity and want to give people a reason to smile during such a tough time for the country.”
Jones has named a strong side which will be captained by fly-half Owen Farrell and includes centurion Ben Youngs at scum-half.
Prop Ellis Genge comes into the front row alongside hooker Jamie George and tighthead Will Stuart, who also makes his first start.
England squad to face Georgia
15. Elliot Daly (Saracens, 43 caps)
14. Jonathan Joseph (Bath Rugby, 51 caps)
13. Ollie Lawrence (Worcester Warriors, 1 cap)
12. Henry Slade (Exeter Chiefs, 30 caps)
11. Jonny May (Gloucester Rugby, 57 caps)
10. Owen Farrell (c) (Saracens, 83 caps)
9. Ben Youngs (Leicester Tigers, 100 caps)
1. Ellis Genge (Leicester Tigers, 19 caps)
2. Jamie George (Saracens, 50 caps)
3. Will Stuart (Bath Rugby, 4 caps)
4. Charlie Ewels (Bath Rugby, 16 caps)
5. Joe Launchbury (Wasps, 65 caps)
6. Maro Itoje (Saracens, 39 caps)
7. Jack Willis (Wasps, uncapped)
8. Billy Vunipola (Saracens, 52 caps)
16. Tom Dunn, (Bath Rugby, 1 cap)
17. Mako Vunipola (Saracens, 60 caps)
18. Kyle Sinckler (Bristol Bears, 36 caps)
19. Ben Earl (Bristol Bears, 4 caps)
20. Tom Curry (Sale Sharks, 24 caps)
21. Dan Robson (Wasps, 3 caps)
22. Max Malins (Bristol Bears, uncapped)
23. Joe Marchant (Harlequins, 3 caps)
In the second row Charlie Ewels and Joe Launchbury pack down, and with no lock replacements, might have to go the full 80.
Billy Vunipola keeps his No8 shirt and in the centres Henry Slade and Ollie Lawrence will combine after the Worcester star made his debut in their Six Nations win in Rome.
Jonathan Joseph is moved back out to the wing and Elliot Daly is fit to take his spot at full-back in a back three that also includes Jonny May.
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