MANUEL NEUER and Leon Goretzka are OUT of Germany's Nations League against England with Covid.
Gareth Southgate's Three Lions host their arch rivals at Wembley on Monday.
But Germany have suffered a squad setback following the news of Goretzka, 27, and Neuer's absence.
The Bayern Munich duo will also miss Friday's match at home to Hungary as a result.
Hoffenheim's Oliver Baumann, 32, will replace keeper Neuer, 36, and further call-ups will be announced in due course.
England have also been hit by injury woe after Manchester City midfielder Kalvin Phillips was forced to pull out due to a shoulder problem.
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He was replaced by Liverpool's Jordan Henderson, 32, who has recovered from a knock quicker than anticipated.
Henderson missed the last three games in all competitions for the Reds after struggling with a hamstring problem.
His setback initially saw him fail to be named in the latest 28-man squad.
But after Phillips, 26, was withdrawn, Southgate has turned to ex-Sunderland anchorman Henderson.
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England play Italy in Milan's San Siro – a rematch of the European Championship final.
And England confirmed Henderson's arrival in a statement.
The decision was made to call-up Henderson after he came through a number of workout sessions over the weekend.
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